Suitability of GaP nanoparticles as a surface-assisted laser desorption/ionization mass spectroscopy inorganic matrix and their soft ionization ability.
نویسندگان
چکیده
Surface-assisted laser desorption/ionization time-of-flight mass spectrometry (SALDI-TOF-MS) using GaP nanoparticles (NPs) prepared by a gas evaporation method was investigated on poly(ethylene glycol)s (PEGs). The mass spectra of PEG and survival yield measurements suggested that larger GaP NPs have a quite high soft ionization ability.
منابع مشابه
Functionalized nanoparticles and nanostructured surfaces for surface-assisted laser desorption/ionization mass spectrometry.
Surface-assisted laser desorption/ionization time-of-flight mass spectrometry (SALDI-TOF-MS) using nanoparticles (NPs) and nanostructured surfaces as the LDI-assisting nanomaterials is a soft ionization technique that features minimal fragmentation of analytes. As compared to traditional matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) using organic ma...
متن کاملSemiconductor Nanomaterials-Based Fluorescence Spectroscopic and Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometric Approaches to Proteome Analysis
Semiconductor quantum dots (QDs) or nanoparticles (NPs) exhibit very unusual physico-chemcial and optical properties. This review article introduces the applications of semiconductor nanomaterials (NMs) in fluorescence spectroscopy and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for biomolecule analysis. Due to their unique physico-chemical and optical properties, s...
متن کاملOne-pot synthesis of dopamine dithiocarbamate functionalized gold nanoparticles for quantitative analysis of small molecules and phosphopeptides in SALDI- and MALDI-MS.
The sensitivity and efficiency of SALDI-MS or MALDI-MS is mainly dependent on the nature of matrix. A novel approach is proposed for one-pot synthesis of dopamine dithiocarbamate-functionalized gold nanoparticles (DDTC-Au NPs). Their application to quantification of small molecules by surface assisted laser desorption/ionization time-of-flight mass spectrometry (SALDI-TOF-MS) and rapid identifi...
متن کاملLaser desorption and matrix-assisted laser desorption/ionization mass spectrometry of 29-kDa Au:SR cluster compounds.
Positive and negative ions generated by laser-based ionization methods from three gold:thiolate cluster compounds are mass analyzed by time-of-flight mass spectrometry. The three compounds have similar inorganic core masses ( approximately 29 kDa, approximately 145 Au atoms) but different n-alkanethiolate ligands associated with each cluster compound (Au:SR, R = butane, hexane, dodecane). Irrad...
متن کاملIntact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass spectrometry
We have investigated the capability of nanoparticle-assisted laser desorption ionization mass spectrometry (NP-LDI MS), matrix-assisted laser desorption ionization (MALDI) MS, and gas cluster ion beam secondary ion mass spectrometry (GCIB SIMS) to provide maximum information available in lipid analysis and imaging of mouse brain tissue. The use of Au nanoparticles deposited as a matrix for NP-L...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Analyst
دوره 138 4 شماره
صفحات -
تاریخ انتشار 2013